One piece sealing reservoir for an insulin infusion pump

ABSTRACT

A novel one-piece fluid reservoir assembly for use in conjunction with an insulin infusion pump. The single piece fluid reservoir assembly includes a barrel body, a male luer fitting integral with the barrel body, a sealing surface integral with the barrel body, the sealing surface for sealing against the pump housing when the fluid reservoir assembly is inserted into the pump housing. Further, the barrel includes, as part of the one-piece fluid reservoir assembly, threads for engagement with threads on an opening in the fluid pump so that the fluid assembly can be inserted into the fluid pump, engage the threads and rotation therewith will locate the fluid reservoir assembly within the pump. Thereafter, a piston in the pump may be incrementally advanced to act upon a plunger in the barrel assembly to force a fluid within the barrel assembly through the male luer fitting and through a conduit engaged therewith to a remote infusion set.

This application incorporates by reference and is a continuation-in-partof U.S. patent application Ser. No. 11/231,737, filed Sep. 21, 2005.

FIELD OF THE INVENTION

Fluid reservoirs for use in conjunction with insulin pumps, namely,one-piece fluid reservoirs that include a male luer fitting and can sealto a housing of the insulin pump

BACKGROUND OF THE INVENTION

Infusion pumps are provided for diabetic patients to allow for theinfusion into the body of the patient of a regulated amount of insulinor other medication. Existing pumps provide a piston for acting on afluid reservoir and for urging fluid, such as insulin, from thereservoir through a conduit to an infusion set and into a patient.

Some of the existing infusion pumps, such as that illustrated in U.S.Pat. No. 6,248,093 (incorporated herein by reference), have an O-ring orother means for providing waterproof or water resistant sealing betweenthe fluid reservoir, insertable into the pump, and the pump housing. Byproviding a waterproof or water resistant engagement between aninsertable fluid reservoir and the housing, the pump user may engage inactivities, such as showering or other behavior that will subject thepump to water. It can be appreciated that the pump and reservoircombination would, advantageously, be water resistant.

Currently, fluid reservoirs that are used with water resistant pumpshave a septum sealed reservoir or a luer nosed reservoir. A reservoirhaving a septum requires engagement with a piercing member to pierce theseptum and provide fluid to a conduit for delivery to an infusion pump.The current reservoirs having a male luer fitting integral therewith,require a separate piece, engageable to the fluid reservoir for adaptingthe fluid reservoir to the water resistant pump. Thus, both of thecurrent types described need a separate piece, either with or without apiercing member, to adapt the fluid reservoir in water sealing relationto the pump housing. While there are some advantages to thisarrangement, Applicants have found advantages in providing in a singlepiece, integral unit, a fluid reservoir with a male luer fitting at aremoved end thereof, which one-piece reservoir is adapted to fit inwater sealing relation to an opening in a pump housing.

It is more convenient for a consumer to use with a single piece ratherthan having to engage one piece (an adaptor) to another (a fluidreservoir) and then the combined assembly to a pump housing. Further,there are some advantages in the manufacturing process for providing asingle piece of Applicants' novel design. Further, advantages resultfrom Applicants' use of a single piece design, combined with a luerfitting, which luer fitting can be adapted to receive a needle forremoving fluid from a larger insulin container, which same luer fittingmay subsequently, after the reservoir is engaged with the pump, accept acommon female lure fitting attached to a conduit having an insulin setat the removed end thereof.

Applicants provide a novel one-piece fluid reservoir for engagement withan infusion pump, which one-piece fluid reservoir will achieve, in asingle unitary piece, a number of functions. Some of these functions,achieved in a one-piece fluid reservoir engageable with an infusionpump, and the associated structure include the following:

SUMMARY OF THE INVENTION

These and other objects are provided in a fluid reservoir assembly forengaging a fluid pump, the pump having a housing, a fluid reservoirchamber, a threaded, cylindrical reservoir housing chamber opening, anda piston to act on the fluid reservoir assembly when the fluid reservoiris in the reservoir chamber, the fluid reservoir assembly comprising aone-piece barrel assembly, the one-piece barrel assembly including acylindrical barrel portion having a barrel diameter and having a firstopen end and a second end, a male luer fitting integral with the secondend of the barrel portion, the male luer fitting having an opening at aremoved end thereof, the one piece barrel assembly including a neckportion integral with the barrel portion, the neck portion includingthreads dimensioned to engage the threads of the reservoir housingchamber opening, the one piece barrel assembly including a cylindricalsealing surface dimensioned to lay adjacent the reservoir housingchamber opening of the pump housing in fluid sealing relation, thecylindrical sealing surface integral with the neck, and a plungerdimensioned for slideable receipt into the open end of the one-piecebarrel assembly; thread segments to engage the female threads in thehousing or case of the infusion pump to hold the fluid reservoir inplace; a sealing surface to seal to the O-ring in the case of theinfusion pump to help seal out water; detents to releasably andlockingly engage recesses in the case of the infusion pump to preventaccidental unscrewing of the fluid reservoir; vent port(s) to permitpressure in the housing or case of the infusion pump to adjust to theexternal atmosphere; a small orifice opening in the luer end of thereservoir to allow flow of medication from the reservoir while providingadequate resistance to flow so that the pump can sense, the flow ofmedication and measure the quantity of medication delivered; tabs toassist in holding the reservoir while screwing it into the pump; and aplunger and rod with threads adapted to prevent the rod from becomingstuck in the plunger and thus difficult to remove after filling thereservoir.

The one-piece sealing reservoir typically provides a 1.8 ml, 3.0 ml orother capacity reservoir intended for use in a portable infusion pumpused for delivery of medication, such as insulin. The fluid reservoirprovides a common male luer connection which allows the patient usingthe infusion pump to connect it to their choice of infusion deliverydevices that have a female luer receptacle.

BRIEF DESCRIPTION OF THE DRAWINGS

FIG. 1 illustrates an exploded view of applicants' novel one-piece fluidreservoir assembly which may also contain a plunger engagement rod, inperspective view.

FIG. 2 illustrates applicants' novel fluid reservoir, including thefluid reservoir assembly with the plunger rod engaging the plungerthereof, in cross-section elevational view.

FIG. 3 illustrates a close-up detail view, in perspective, of the secondend of the barrel portion showing the integral neck sealing surface,tabs, threads and other related structure, including the male luerfitting in fluid engagement with the interior of the barrel.

FIG. 4 is a similar perspective view of the assembly of FIG. 3, takenfrom a different angle.

FIG. 5 is a perspective view from the front of applicants' barrelportion of the fluid reservoir assembly showing the vent ports integraltherewith and the filter medium bonded or sealed to the external wallsof the ports.

FIG. 6 shows the plunger with an internal threaded area and the rod withthe threaded area for threadable engagement with the plunger,illustrating the novel flat ends of the threads in cross-sectional view.

FIG. 7 is a cross-sectional elevational view, partially cut away,showing the manner in which applicants' fluid reservoir assembly engagesa housing of a pump having the reservoir chamber and a reservoir chamberopening.

FIG. 8 illustrates the manner in which applicants' fluid assembly may beused to fill an empty fluid reservoir for insertion into the fluid pump.

FIG. 9 illustrates in a top elevational view, partially cut away, themanner in which applicants' fluid reservoir assembly engages thereservoir chamber of the housing of the pump.

FIG. 10 illustrates in a side elevational view, applicants' novelpump/infusion set assembly wherein the fluid reservoir engages the pumpand an infusion set having a conduit with a female luer fitting at theend thereof to engage the male luer fitting of the fluid reservoir.

FIGS. 11A-11D illustrate various views of an alternate preferredembodiment of Applicants' device.

DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS

FIG. 1 shows a fluid reservoir assembly 10 with a luer portion 20, aneck portion 40, and a barrel portion 60. A plunger 70 slideably engagesthe inner surface of the barrel portion, and a plunger engagement rod 90removably engages the plunger. The barrel portion 60 holds themedication to be delivered and receives the plunger, which will matewith a drive piston from the infusion pump (see FIG. 9).

FIG. 2 shows the assembled reservoir 10, plunger 70 and rod 90 in crosssection. The plunger 70 has a plunger threaded area 72 to engage with arod thread area 94 of the rod 90. The plunger typically is adapted toreceive one or more O-rings 74 on an outer surface thereof to slideablyseal to the barrel portion 60 of the reservoir assembly 10.

During filling of the reservoir 10 illustrated in FIG. 8, a handle 92 ofthe rod 90 in used to draw the plunger 70 back and suck medication froma larger, typically septum sealed, container 106 into the barrel area60. After filling the reservoir 10, the rod 90 is unscrewed from theplunger 70 and discarded.

FIG. 3 shows details of the luer area 20 and neck area 40. The luer area20 consists of a standard male luer 22, and optionally threads 26 toreceive a threaded female luer receptacle from an infusion delivery set.The standard male luer and associated structure (threads, etc.) may bedimensioned according to IS0594-1 and 594-2 (incorporated herein byreference), provided, however, the opening dimensions as set forthbelow.

The filled reservoir 10 is inserted, axially, into the infusion pump,barrel end first after removal of the rod 90. When the reservoir 10 isfully inserted into the infusion pump, the thread segments 44 located onthe neck 42 engage threads in the infusion pump. Optionally, tabs 24 areprovided to facilitate the tightening and loosening of the reservoir inthe infusion pump. Sealing surface 30 is dimensioned slightly less thanthe reservoir chamber opening assembly to seal the reservoir 10 to anO-ring (or O-rings) or other functional equivalents located in theinfusion pump housing opening (see FIG. 9). The sealing of the reservoirto the case housing of the infusion pump provides a watertight or waterresistant infusion pump/reservoir assembly permitting the patient towear the infusion pump during swimming, showering or other activitieswhich might otherwise cause water to enter the case and damage theelectronic components. Detents 28 may engage recesses in the infusionpump case to prevent accidental unscrewing of the reservoir from theinfusion pump. Detents 28 may be integral with the walls of sealingsurface 30.

Existing infusion pumps have a means of measuring the volume ofmedication flowing from the fluid reservoir by determining motion of thedrive piston. They sometimes use a sensor located in the drive pistonassembly to detect the movement of the plunger in the reservoir. For thesensor to detect the movement of the drive piston, there must beresistance to the flow of medication and hence to the movement of theplunger. Luer 22 has a novel orifice opening 32 which allows medicationto flow from the reservoir while providing resistance to the flow. Thesize of the orifice opening 32 is novel as being very small, from 0.003″to 0.020″ (preferred range 0.005-0.010″) in diameter. This smalldiameter of the orifice opening 32 provides a restriction to flowsufficient for the infusion pump to measure the quantity of medicationdelivered.

FIG. 4 is a view of the luer area 20 showing at least one vent port 34.

FIG. 5 shows a filter medium 36, typically hydrophobic, bonded into thevent port 34. While the infusion pump/reservoir assembly is sealed toprevent water from entering the interior of the case, there should bestructure provided to let the internal pressure in the case adjust tothe external atmosphere. If the internal pressure in the infusion pumpis different from the external atmosphere, the accuracy of medicationdosing may be effected. To allow the internal pressure of the infusionpump to adjust to the external atmosphere, vent ports 34 are provided inluer area 20 of reservoir 10. Vent ports 34 are covered typically by ahydrophobic filter material 36. Hydrophobic material permits gas to passthrough the material while resisting the passage of water or otherliquids, thus permitting water resistant venting. The hydrophobicmaterial may be welded to the reservoir by ultrasonic or heat staking orit may be bonded by other means.

FIG. 6 shows thread area 72 of plunger 70 and thread area 94 of rod 90.The threads 72 of the plunger 70 end in a flat end 76. The threads 94 ofthe rod 90 also end in a similarly dimensioned flat end 98. When the rod90 is screwed into the plunger 70, the flat ends 76 and 98 butt againsteach other before threads 72 and 94 can tighten against one another.Stopping the threads in this manner prevents the rod 90 from becomingstuck in the plunger 70 and difficult to remove after filling thereservoir 10.

FIG. 7 shows an exploded view of applicants' novel fluid reservoir 10,after the rod has been removed therefrom and after it has been filled,as it engages the housing H of a pump.

Housing H is seen to include a reservoir chamber RC and a reservoirchamber opening RCO. The reservoir chamber opening has detent openings28A on the walls thereof for receipt of applicants' detents 28. Threads44, typically in the neck area of the fluid reservoir, are provided toengage threads 44A on the reservoir chamber opening so as to positionthe fluid-filled fluid assembly 10 within the reservoir chamber. A motorM can drive a drive piston DP axially along the longitudinal axis of thebarrel portion 60 so as to engage the piston and drive fluid out of theluer fitting and into a conduit 110 as set forth in FIG. 10.

FIG. 8 illustrates the use of applicant's fluid reservoir assembly toengage a needle assembly 100, which needle assembly has engagedtherewith in fluid sealing relation a needle 102. Needle 102 has aremoved end with a small orifice in it and is hollow. Needle assembly100 typically includes a female luer fitting 104, which female luerfitting is designed to and dimensioned to be received snugly in fluidsealing relation to male luer portion 20 of barrel portion of reservoir10.

With the fluid reservoir 10 having needle assembly 100 engaged therewithand, with plunger engagement rod 90 engaged with plunger 70, and plunger70 in a full forward position against the walls defining the end of theluer barrel portion 60 (which contains male luer portion 20), user caninsert needle 102 through a septum of a fluid (typically insulin)container 106. Retraction of plunger engagement rod 90 in the directionindicated in FIG. 8 will allow fluid to be withdrawn from container 106into fluid reservoir 10. When plunger 70 is at or near the removed openend of barrel portion 60, plunger engagement rod 90 can be rotated andremoved from the plunger. Because of applicant's novelflat-end-to-flat-end threaded engagement between plunger engagement rod90 and plunger 70, plunger 70 should not rotate in the barrel and thuswill make rotational disengagement of plunger from the rod easy. Withplunger engagement rod 90 discarded, reservoir 10 can be assertedaxially into cylindrical pump as illustrated in FIGS. 7 and 9.

Applicant's novel reservoir has a barrel portion, typically of adiameter sufficient to pass through reservoir chamber opening and intothe reservoir chamber, aligning with the walls of the chamber so as topresent a barrel assembly longitudinal axis aligned with thelongitudinal axis of the drive piston. When applicant's reservoir 10 isinserted into housing H, such as a Mini-Med Model MMT-511, threads 44Awill engage threads 44 of reservoir 10, and upon engagement andcontinued rotation of reservoir 10, the reservoir will be drawn intoreservoir chamber RC a distance to place sealing surface 30 adjacentO-rings or other sealing means at reservoir chamber opening RCO.Moreover, applicant's detents 28 on the walls of sealing surface 30,typically small projections, may engage cutouts 28A in the walls ofreservoir chamber opening RCO as illustrated in FIG. 7.

FIG. 10 shows pump P held in place by a belt B on a user. Pump P showsan infusion set assembly 110 having a fluid conduit 112 engagedtherewith. At a near end of the fluid conduit 112 is a female luerfitting 114 for snugly engaging applicant's fluid reservoir 10. A femaleluer assembly 114 may have threads 114A at a base thereof for threadedengagement with luer threads 26 of fluid reservoir 10. Fluid from thefluid reservoir 10 will be urged, by incremental advances of drivepiston DP, through the male and female luer fittings and conduit 112 toan infusion set 116 for infusion into the body of the user in ways knownin the trade.

FIGS. 11A-11D illustrate an alternate preferred embodiment ofApplicants' one piece unitary fluid reservoir 10 a. As with the previousembodiments, a single piece provides for multiple functions, some ofwhich were carried out with multiple pieces of the prior art. Here, acylindrical reservoir 60 has shoulders 60 a sloping inward to anoutwardly directed open ended luer 22 and a neck 42 having a diametersmaller than that of the reservoir 60 extending outward from theshoulders. Neck 42 is cylindrical and on an inner surface thereof may,optionally, have luer locking threads 26. Luer locking threads 26 areprovided so that lure 22, also typically at least partially within thecylindrical walls of neck 42, may receive a female fitting snuglythereupon.

Neck 42 is seen to provide support for cylindrical O-ring seal surface30, which has a diameter larger than the diameter of neck 42. O-ringseal surface 30 has a diameter sufficient to be snugly received withinthe pump opening as seen in cross-section in FIG. 11 b, against O-ring51. A base 31 trending substantially perpendicular to the outer walls ofneck 42 provides support for O-ring seal surface 30. Moreover, base 31may include vent ports 34 as seen in FIG. 11 a. Vent ports 34 may becovered, typically on the outer surface, by a filter material 36 as setforth in previous embodiments. Threaded segments 44 a/44 b may beprovided on neck 42 functioning as in previous embodiment.

With reference to FIG. 11 b, it is seen that threaded segments 44 a/44 bmay engage the infusion case. It can be seen that O-ring seal surface 30will seat snugly against O-ring 51 providing a fluid-tight seal wherereservoir 60 engages the housing of the infusion pump. Moreover, in FIG.11 b, it can be seen how vent 34 provides for breathing between theinterior of the pump housing and the surrounding environment, to takeinto account changes in external or internal air pressure. Detents 28may be seen to be slightly raised nubs on the O-ring seal surface 30outward from where the seal surface joins the O-ring 51.

In an alternate preferred embodiment 10 a, Applicants are seen toprovide a cylindrical extension 120. Cylindrical extension 120,typically, is a cylindrical member of about the same diameter as andindeed may be a continuation outward of O-ring seal surface 30, as bestseen in FIGS. 11 a and 11 b. In FIG. 11 b, it will be seen thatcylindrical extension 120 may be seen to be that portion standing abovethe pump housing walls when the reservoir is properly threadablyinserted and seated into the pump housing. The cylindrical extension 120provides for protection of the luer coupling and prevents its accidentaltwisting, and may also provide a surface which the user may grasp.

It may be seen that cylindrical extension 120 includes, in oneembodiment, a multiplicity of ribs 122 circumferentially spaced on thewalls thereof. The multiplicity of ribs 122 provide for strengthening ofthe outer walls thereof, and additional surface area for the user in themanipulation, insertion, and removal of unit 10 a from a pump housing.The slight smooth, rounded, outward projection of ribs 122 may be seen,for example, in the cross-sectional view of FIG. 11 b. Moreover, it isseen in FIG. 11 b how the ribs 122 may extend slightly beyond upperwalls 120 a of the unit 10 a. Projections 122 a are seen to have arounded, smooth profile.

At a near end of ribs 122, relative to the pump housing as seen in FIG.11 b, the ribs may terminate in flat end or walls 122 b. Flat end 122 bof ribs 122 may sit snugly and substantially flush against the outerwalls of the pump when the reservoir is inserted (seated) into thehousing, as seen in FIG. 11 b.

Also with reference to FIG. 11 b, it may be seen how the removedterminus of neck 42 has the luer 22 extending beyond it. Then, extendingbeyond or outward from the removed end of luer 22 is the corrugatedupper perimeter 120 a of cylindrical extension 120. In this fashion,cylindrical extension 120 provides some protection to the removed end ofluer 22.

Ribs 122 are typically spaced about every 2.7 mm along a cylindricalsection having an outer diameter about 15.6 mm (circumference of about49 mm). The ribs stand up about 0.5 mm above the upper perimeter 102 aof the cylindrical extension 120. The ribs are about 1.5 mm wide (withthe fillets). There are no opposing surfaces to measure. Moreover, inFIG. 11 d, a top view looking down, it will be seen that ribs 122 have asmooth, curved or rounded outer surface for ergonomic advantage.

Although the invention has been described with reference to specificembodiments, this description is not meant to be construed in a limitedsense. Various modifications of the disclosed embodiments, as well asalternative embodiments of the inventions, will become apparent topersons skilled in the art upon the reference to the description of theinvention. It is, therefore, contemplated that the appended claims willcover such modifications that fall within the scope of the invention.

1. An assembly for the delivery of insulin to a diabetic patient, theassembly comprising: a pump, the pump having a reservoir chamber, adrive piston, and a reservoir chamber opening, the reservoir chamberopening with O-ring sealing member thereon; and a unitary, one piecefluid reservoir comprising a cylindrical barrel portion having a barreldiameter and having a first end and a second end having shouldersthereon; a male luer fitting integral with the shoulders of the secondend of the barrel portion, the male luer fitting having an opening at aremoved end thereof, the shoulders of the cylindrical barrel portionsupporting and rigidly integral with a cylindrical neck portion, theneck portion including integral outward projecting threads dimensionedto engage the threads of the reservoir housing chamber opening, thefluid reservoir further including a cylindrical sealing surfacedimensioned to lay adjacent the reservoir chamber opening of the pump influid sealing relation to the O-ring sealing member of the pump, thecylindrical sealing surface joined rigidly non-moveably and integral tothe neck portion by a base, the fluid reservoir further including anopen ended cylindrical extension, extending outward from and rigidly andnon-moveably joining the cylindrical sealing surface, the cylindricalextension having an outer surface, an inner volume, and an upperperimeter; a plunger dimensioned for slideable receipt into the firstend of the cylindrical barrel section; a conduit including a first endadapted to engage the male luer fitting of the fluid reservoir, theconduit having a second end; and an infusion set, for engagement withthe second end of the conduit, the infusion set for feeding fluid fromthe reservoir, through the engaged luer fittings and the conduit intothe infusion set and into the person to which the infusion set isengaged.
 2. The assembly of claim 1, wherein the upper perimeter of thecylindrical extension of the unitary, one-piece fluid reservoir extendsbeyond the removed end of the male luer fitting.
 3. The assembly ofclaim 1, wherein the outer surface of the cylindrical extension includesa multiplicity of ribs thereon.
 4. The assembly of claim 1, wherein thecylindrical sealing surface and the cylindrical extension have about thesame diameter.
 5. The assembly of claim 1, wherein the upper perimeterof the cylindrical extension of the unitary, one-piece fluid reservoirextends beyond the removed end of the male luer fitting; wherein theouter surface of the cylindrical extension includes a multiplicity ofribs thereon; and wherein the cylindrical sealing surface and thecylindrical extension have about the same diameter.
 6. The assembly ofclaim 1, wherein the cylindrical sealing surface of the unitary barrelincludes detents on the walls thereof.
 7. The assembly of claim 6,wherein the upper perimeter of the cylindrical extension of the unitary,one-piece fluid reservoir extends beyond the removed end of the maleluer fitting; wherein the outer surface of the cylindrical extensionincludes a multiplicity of ribs thereon; and wherein the cylindricalsealing surface and the cylindrical extension have about the samediameter.
 8. The assembly of claim 1, wherein the upper perimeter of thecylindrical extension is corrugated.
 9. A one-piece, unitary, undividedfluid reservoir comprising: a cylindrical barrel portion having a barreldiameter and having a first end and a second end having shouldersthereon; a male luer fitting integral with the shoulders of the secondend of the barrel portion, the male luer fitting having an opening at aremoved end thereof, the shoulders of the cylindrical barrel portionsupporting and rigidly integral with a cylindrical neck portion, theneck portion including integral outward projecting threads dimensionedto engage the threads of the reservoir housing chamber opening, thefluid reservoir further including a cylindrical sealing surfacedimensioned to lay adjacent the reservoir chamber opening of the pump influid sealing relation to the O-ring sealing member of the pump, thecylindrical sealing surface joined rigidly non-moveably and integral tothe neck portion by a base, the fluid reservoir further including anopen ended cylindrical extension, extending outward from and rigidly andnon-moveably joining the cylindrical sealing surface, the cylindricalextension having an outer surface, an inner volume, and an upperperimeter;
 10. The fluid reservoir of claim 9, wherein the upperperimeter of the cylindrical extension extends beyond the removed end ofthe male luer fitting.
 11. The fluid reservoir of claim 9, wherein theouter surface of the cylindrical extension includes a multiplicity ofribs thereon.
 12. The fluid reservoir of claim 9, wherein thecylindrical sealing surface and the cylindrical extension have about thesame diameter.
 13. The fluid reservoir of claim 9, wherein the upperperimeter of the cylindrical extension extends beyond the removed end ofthe male luer fitting; wherein the outer surface of the cylindricalextension includes a multiplicity of ribs thereon; and wherein thecylindrical sealing surface and the cylindrical extension have about thesame diameter.
 14. The fluid reservoir of claim 9, wherein thecylindrical sealing surface of the unitary barrel includes detents onthe walls thereof.
 15. The fluid reservoir of claim 14, wherein theupper perimeter of the cylindrical extension extends beyond the removedend of the male luer fitting; wherein the outer surface of thecylindrical extension includes a multiplicity of ribs thereon; andwherein the cylindrical sealing surface and the cylindrical extensionhave about the same diameter.
 16. A kit for providing insulin to apatient through an infusion set engaged with the patient, the kitcomprising: a pump, the pump having a reservoir chamber, a drive piston,and a reservoir chamber opening, the reservoir chamber opening withO-ring sealing member thereon; and a unitary, one piece fluid reservoircomprising a cylindrical barrel portion having a barrel diameter andhaving a first end and a second end having shoulders thereon; a maleluer fitting integral with the shoulders of the second end of the barrelportion, the male luer fitting having an opening at a removed endthereof, the shoulders of the cylindrical barrel portion supporting andrigidly integral with a cylindrical neck portion, the neck portionincluding integral outward projecting threads dimensioned to engage thethreads of the reservoir housing chamber opening, the fluid reservoirfurther including a cylindrical sealing surface dimensioned to layadjacent the reservoir chamber opening of the pump in fluid sealingrelation to the O-ring sealing member of the pump, the cylindricalsealing surface joined rigidly non-moveably and integral to the neckportion by a base, the fluid reservoir further including an open endedcylindrical extension, extending outward from and rigidly andnon-moveably joining the cylindrical sealing surface, the cylindricalextension having an outer surface, an inner volume, and an upperperimeter; wherein the upper perimeter of the cylindrical extension ofthe unitary, one-piece fluid reservoir extends beyond the removed end ofthe male luer fitting; wherein the outer surface of the cylindricalextension includes a multiplicity of ribs thereon; wherein thecylindrical sealing surface and the cylindrical extension have about thesame diameter; wherein the cylindrical sealing surface of the unitarybarrel includes detents on the walls thereof; and wherein the upperperimeter of the cylindrical extension is corrugated; a plungerdimensioned for slideable receipt into the first end of the unitarybarrel; a conduit including a first end adapted to engage the male luerfitting of the fluid reservoir, the conduit having a second end; and aninfusion set, for engagement with the second end of the conduit, theinfusion set including a cannula capable of subcutaneous placement forfeeding fluid from the reservoir, through the engaged luer fittings andthe conduit into the infusion set and into the person to which theinfusion set is engaged.